Muscle Strength, Bone Mass, and Age-Related Bone Loss
نویسندگان
چکیده
منابع مشابه
Age-Related Loss of Muscle Mass and Strength
Age-related muscle wasting and increased frailty are major socioeconomic as well as medical problems. In the quest to extend quality of life it is important to increase the strength of elderly people sufficiently so they can carry out everyday tasks and to prevent them falling and breaking bones that are brittle due to osteoporosis. Muscles generate the mechanical strain that contributes to the...
متن کاملStructural basis of growth-related gain and age-related loss of bone strength
If bone strength was the only requirement of skeleton, it could be achieved with bulk, but bone must also be light. During growth, bone modelling and remodelling optimize strength, by depositing bone where it is needed, and minimize mass, by removing it from where it is not. The population variance in bone traits is established before puberty and the position of an individual's bone size and ma...
متن کاملEstrogen and bone-muscle strength and mass relationships.
The largest voluntary loads on bones come from muscles. To adapt bone strength and mass to them, special strain threshold ranges determine where modeling adds and strengthens bone, and where remodeling conserves or removes it, just as different thermostat settings control the heating and cooling systems in a house. If estrogen lowers the remodeling threshold, two things should occur. First, at ...
متن کاملEssential amino acid supplements increase muscle weight, bone mass and bone strength in adult osteoporotic rats.
Protein undernutrition is known to play an important role in the pathogenesis of osteoporotic fracture in elderly. The mechanisms underlying the bone loss in protein undernutrition appeared to be related to an uncoupling between increased bone resorption and bone formation. This was associated with decreased plasma IGF-I levels, with anoestrus and decreased muscle mass. Reversibility of protein...
متن کاملPathophysiology of age-related bone loss and osteoporosis.
Aging is associated with significant bone loss in women and in men [1]. Fig. 1, which draws on numerous cross-sectional and longitudinal studies using areal bone mineral density (aBMD) by dual energy x-ray absorptiometry (DXA), depicts the overall pattern of bone loss in both sexes. The menopause in women is associated with a rapid loss of trabecular bone, as is present in the vertebrae, pelvis...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 1997
ISSN: 0884-0431
DOI: 10.1359/jbmr.1997.12.10.1547